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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
12.12
Human Site:
Y66
Identified Species:
26.67
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
Y66
L
E
S
K
L
V
K
Y
F
S
R
Q
L
S
C
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
D63
Q
E
R
N
A
E
L
D
G
F
P
Q
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
L13
S
L
L
F
C
S
N
L
G
G
N
L
S
K
Q
Dog
Lupus familis
XP_853953
898
99758
Y83
L
E
A
K
L
V
R
Y
I
C
K
Q
Q
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
Y66
L
E
S
K
L
V
K
Y
F
S
R
Q
L
S
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
S14
G
S
S
A
E
G
A
S
L
F
N
G
D
M
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
Y65
L
E
G
K
L
V
K
Y
F
S
R
Q
L
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
Honey Bee
Apis mellifera
XP_393005
895
100160
V63
K
L
Y
S
K
Q
L
V
T
K
A
K
L
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
P29
S
V
S
V
T
G
A
P
P
P
H
Y
D
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
20
0
53.3
N.A.
100
N.A.
N.A.
0
6.6
N.A.
86.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
20
0
73.3
N.A.
100
N.A.
N.A.
0
6.6
N.A.
86.6
N.A.
0
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
0
19
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
28
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
19
0
0
% D
% Glu:
0
46
0
0
10
10
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
28
19
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
19
0
0
19
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
37
10
0
28
0
0
10
10
10
0
10
0
% K
% Leu:
37
19
10
0
37
0
19
10
10
0
0
10
46
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
10
10
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
46
10
10
10
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
28
0
0
10
0
% R
% Ser:
19
10
37
10
0
10
0
10
0
28
0
0
10
37
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
37
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
37
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _